This standard applies to the classification and labeling for substances or mixtures of acute toxicity. The current version is an update of its initial one published on 12 Oct 2006, based on Globally Harmonized System of Classification and Labeling of Chemicals, ST/SG/AC. 10/31/Rev.2 (GHS Rev.2 released in 2007).

Acute toxicity refers to those adverse effects occurring following oral or dermal administration of a single dose of a substance, or multiple doses given within 24 hours, or an inhalation exposure of 4 hours.