Taiwan will launch its existing chemical substance Phase 1 registration on September 1, 2015. Many potential registrants have been actively preparing themselves and it is strongly recommended to begin preparation and collection of information to be used for registration as soon as possible. This is of course to ensure full compliance to the regulation when it is enforced and also to reduce risks that may impact the outcome of business deals. Despite the pending implementation of new regulatory requirements there are still are some unanswered questions and ambiguous points that are yet to be clarified. Thus, this article has been prepared to help clarify some of these uncertainties.