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Japan Announces Update to PAC List, 6 Substances Added and Three Removed

On April 1, 2020, the Japanese Ministry of Economy, Trade and Industry (METI) announced that six substances [1] will be added to the list of Priority Assessment Chemical Substances (PACs) under the country’s Chemical Substance Control Law (CSCL) [2]. Another notice issued on the previous day made public the removal of three substances [3] from it.

The details of changes to the list are presented in the table below.


Substance   name

Substances added into list

 

Hydrogen   cyanide

Diethyl   phthalate (DEP)

5-chloro-2-(4-chlorophenoxy)phenol

4,4-diamino-3,3-dichlorodiphenylmethane   [synonym: 4,4'-methanediylbis(2-chloroaniline)]

Mixture of bicyclo[2.2.1]heptane-2,5(or 2,6)-diyldicyanide

Salts   of poly[iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl]   hydrochloride, limited to those formed with addition of a proton to the   nitrogen atom

Substances removed from the list

Pyridine-triphenylborane(1/1)       

N,N-Dimethylpropane-1,3-diyldiamine

Manganese   N,N'-ethylenebis(dithiocarbamate) (synonym: Maneb)

Under the framework of CSCL, certain substances will be selected from general chemical substances and new chemical notifications for risk screening and assessment. Those with potential risks of long-term toxicity for humans or the environment will be designated as PACs. To effectively regulate substances on the list, PACs manufactured/imported in an amount of 1 ton/year or more are subject to specific annual notification requirements.

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