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According to the Gazette on April 1, 2024, Japan added 12 substances to the List of Priority Assessment Chemical Substances (PAC List) following the removal of 5 substances on March 29. This brings the total number of PACs to 225.
The details of changes to the list are presented in the table below.
No. | MITI No. | Chemical Substances Name | |
5 substances removed from the PAC list (now classified as general chemicals)
| 9 | 2-39 | Bromomethane (synonym: Methyl bromide) |
37 | 2-1276 | Nitrilotriacetic acid | |
160 | 5-6110 | 2-tert-Butylamino-4-cyclopropylamino-6-methylthio-1,3,5-triazine | |
237 | 2-139 | Trioctylamine | |
243 | 2-2607 | Salt of N,N-diethyl-N-methyl-2-[(2-methylprop-2-enoyl)oxy]ethan-1-aminium | |
12 substances added into the PAC list | 274 | - | Salt of N,N,N-trimethyl-1-oxiranylmethanaminium |
275 | 2-414 | 3-[(2-Ethylhexyl)oxy]propane-1,2-diol | |
276 | 2-422 | 2-(2-Butoxyethoxy)ethan-1-ol (synonym: Diethylene glycol monobutyl ether) | |
277 | 2-723 | N,N-Dimethylacetamide | |
278 | 2-726 | Ethyl acetate | |
279 | 2-727 | n-Propyl acetate | |
280 | 2-1667 | Reaction products of sodium hydrogen sulfite and (chloromethyl)oxirane and N,N-dimethyldodecan-1-amine, which consists of 3-(N,N-dimethyldodecan-1-aminiumyl)-2-hydroxypropane-1-sulfonate as a major component (80% or more) | |
281 | 2-2807 | Potassium octadecenesulfonate or potassium hydrogen octadecenedisulfonate or potassium hydroxyoctadecanesulfonate or dipotassium octadecenedisulfonate | |
282 | 2-2807 | Potassium hydrogen hexadecenedisulfonate or potassium hydroxyhexadecanesulfonate or potassium hexadecenesulfonate or dipotassium hexadecenedisulfonate | |
283 | 3-1736 | Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate | |
284 | 3-2492 | 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate | |
285 | 5-3881 | 1,4-Dioxacyclohexadecane-5,16-dione |
In addition, there are 6 substances currently under observation, and their status on the PAC list will be decided in the coming years.
No. | MITI No. | Chemical Substances Name |
70 | 3-4280 | Octadecylamine(N-B)triphenylborane |
200 | - | Salts of benzyl(dimethyl)(octyl)ammonium |
242 | 2-1291 | [Dimethyl(octadecyl)azaniumyl]acetate |
246 | 3-1730 | Ethyl 2-phenylpropanoate |
255 | 4-95 | 4,4'-Diamino-3,3'-dichlorodiphenylmethane (synonym: 4,4'-Methylenebis(2-chloroaniline)) |
256 | 4-1715 | Mixture of bicyclo[2.2.1]heptane-2,5(or 2,6)-diyl dicyanide |
According to the evaluation method for priority assessment substances under the Chemical Substance Control Law (CSCL), substances that have a total national import/production volume not exceeding 10 tons or estimated emissions not exceeding 1 ton in the previous year enter an "Observation Period". If a substance remains in the observation period for three consecutive years and is determined to pose no risks to human health or the environment, it will be removed from the PAC list and treated as a general chemical substance.
Manufacturers and importers of PACs are required to report the production and/or import volume, use category, and production site to the Ministry of Economy, Trade and Industry (METI) from April to June each year, following the framework of the CSCL.
It is important to note that the 5 substances removed and the 12 substances added can now be reported as general chemicals this year.
The updated PACs list can be accessed here for reference.
