On July 21, 2022, South Korea’s National Institute of Chemical Safety (NICS) consulted on the draft amendments to the Regulation on Specific Handling Standards for Hazardous Chemicals (hereinafter referred to as the Regulation). The handling standards for each hazardous chemical is stipulated in the Annex of NICS Announcement No.2022-77, which consists of 1147 items (360 more than its 2018 version). One item is for one hazardous chemical, detailing the chemical’s name and CAS number (if any), given number (if any), and the corresponding handling criteria, etc. Any comments are welcome before August 10, 2022. Once these amendments are adopted and released to the public, they will take effect immediately.