The comprehensive management of hazardous chemical substances in Thailand began in 1960s with the publication of Toxic Substances Act of B.E. 2510 (1967). 25 years after that, Thailand government carried out the Hazardous Substances Control Act (HSCA) B.E. 2535 (1992) in order to manage the booming chemical industry. HSCA covered a wider range of hazardous chemicals and raised more requirements on the industry than the Toxic Substances Act, such as notification, registration, application for license, etc.