On June 24, 2020, the Japanese Ministry of Health, Labor and Welfare (MHLW) published a notice [1], announcing to approve adjustments to the lists of poisonous and deleterious chemicals designated under the Poisonous and Deleterious Substances Control Law (PDSCL) [2]. Two arounds of public consultations were held previously.
The official revision is identical to the adjustments proposed in the second round of consultation, as shown in the table below.
Substance Name | CAS No. | |
Substances added into the Poisonous Substances List | Cobalt(II) oxide and preparations containing cobalt(II) oxide | 1307-96-6 |
Dibutyl(dichloro)stannane and preparations containing dibutyl(dichloro)stannane | 683-18-1 | |
Substances added into the Deleterious Substances List | 1-Amino-2-propanol and preparations containing no less than 4% 1-amino-2-propanol | 78-96-6 |
2-Isobutoxyethanol and preparations containing no less than 10% 2-isobutoxyethanol | 4439-24-1 | |
Oxirane-2-ylmethyl＝methacrylate and preparations containing oxirane-2-ylmethyl＝methacrylate | 106-91-2 | |
1-Chloro-4-nitrobenzene and preparations containing 1-chloro-4-nitrobenzene | 100-00-5 | |
2,4-Dichlorophenol and preparations containing 2,4-dichlorophenol | 120-83-2 | |
Nonylphenol and preparations containing no less than 1% nonylphenol | 25154-52-3 | |
1-Vinyl-2-pyrrolidone and preparations containing no less than 10% 1-vinyl-2-pyrrolidone | 88-12-0 | |
Ammonium fluoride and preparations containing ammonium fluoride | 12125-01-8 | |
Sodium fluoride and preparations containing sodium fluoride | 7681-49-4 | |
Benzene-1,4-dicarbonyl dichloride and preparations containing benzene-1,4-dicarbonyl dichloride | 100-20-9 | |
Benzoyl chloride and preparations containing no less than 0.05% benzoyl chloride | 98-88-4 | |
Methanesulfonic acid and preparations containing no less than 0.5% methanesulfonic acid | 75-75-2 | |
Sodium bisulfide and preparations containing sodium bisulfide | 16721-80-5 | |
Disodium sulfide and preparations containing disodium sulfide | 1313-82-2 | |
Substances removed from the Deleterious Substances List | 4-Ethylocta-3-enenitrile and preparations containing 4-ethylocta-3-enenitrile | 29127-85-3 |
3,4-Dimethylbenzonitrile and preparations containing 3,4-dimethylbenzonitrile | 22884-95-3 |
Meanwhile, an adjustment was proposed for the concentration of lithium hydroxide (CAS No.: 1310-66-3) in preparations in the Deleterious Substances List, raising the threshold from 0.3% to 0.5%.
According to the PDSCL, businesses may not engage in the sale of any poisonous/deleterious substance or the manufacture/import of such substance for sales purposes unless they are registered as distributors, manufacturers or importers of poisonous/deleterious substances. Relevant businesses should also employ personnel with specialized certificates.
