On April 28, 2020, the Japanese Ministry of Health, Labor and Welfare (MHLW) published a notice [1] to solicit comments on adjustments to the lists of poisonous and deleterious chemicals designated under the Poisonous and Deleterious Substances Control Law (PDSCL) [2], four months after the first round of consultation [3].
The details of the adjustments are shown in the table below.
Substance Name | CAS No. | |
Substances added into the Poisonous Substances List | Cobalt(II) oxide and preparations containing cobalt(II) oxide | 1307-96-6 |
Dibutyl(dichloro)stannane and preparations containing dibutyl(dichloro)stannane | 683-18-1 | |
Substances added into the Deleterious Substances List | 1-Amino-2-propanol and preparations containing no less than 4% 1-amino-2-propanol | 78-96-6 |
2-Isobutoxyethanol and preparations containing no less than 10% 2-isobutoxyethanol | 4439-24-1 | |
Oxirane-2-ylmethyl＝methacrylate and preparations containing oxirane-2-ylmethyl＝methacrylate | 106-91-2 | |
1-Chloro-4-nitrobenzene and preparations containing 1-chloro-4-nitrobenzene | 100-00-5 | |
2,4-Dichlorophenol and preparations containing 2,4-dichlorophenol | 120-83-2 | |
Nonylphenol and preparations containing no less than 1% nonylphenol | 25154-52-3 | |
1-Vinyl-2-pyrrolidone and preparations containing no less than 10% 1-vinyl-2-pyrrolidone | 88-12-0 | |
Ammonium fluoride and preparations containing ammonium fluoride | 12125-01-8 | |
Sodium fluoride and preparations containing sodium fluoride | 7681-49-4 | |
Benzene-1,4-dicarbonyl dichloride and preparations containing benzene-1,4-dicarbonyl dichloride | 100-20-9 | |
Benzoyl chloride and preparations containing no less than 0.05% benzoyl chloride | 98-88-4 | |
Methanesulfonic acid and preparations containing no less than 0.5% methanesulfonic acid | 75-75-2 | |
Sodium bisulfide and preparations containing sodium bisulfide | 16721-80-5 | |
Disodium sulfide and preparations containing disodium sulfide | 1313-82-2 | |
Substances removed from the Deleterious Substances List | 4-Ethylocta-3-enenitrile and preparations containing 4-ethylocta-3-enenitrile | 29127-85-3 |
3,4-Dimethylbenzonitrile and preparations containing 3,4-dimethylbenzonitrile | 22884-95-3 |
Meanwhile, an adjustment was proposed for the concentration of lithium hydroxide (CAS No.: 1310-66-3) in preparations in the Deleterious Substances List, raising the threshold from 0.3% to 0.5%.
The official revision to the lists is expected to be released in mid-June and implemented in July this year. According to the PDSCL, businesses may not engage in the sale of any poisonous/deleterious substance or the manufacture/import of such substance for sales purposes unless they are registered as distributors, manufacturers or importers of poisonous/deleterious substances. Relevant businesses should also employ personnel with specialized certificates.
