On January 24, 2025, South Korea’s National Institute of Chemical Safety (NICS) announced the updates to the Toxic Chemical Substances List (TCSL) and the GHS Classification List. The updates to TCSL will come into force three months after the publication. The updates to GHS Classification List took effect immediately.
Updates to TCSL
26 chemicals are now designated as toxic chemical substances (Given No. 2025-1-1223 ~ 2025-1-1248), which have been registered under K-REACH and found toxic after hazard assessments. Their chemical names, CAS numbers, and concentration limits in mixtures are made public by NICS Announcement No. 2025-2.
The chemical information of one listed toxic chemical Given No. 97-1-91 has been updated to exclude zinc fulminate.

Manufacturers, importers and handlers, who have operated businesses involving the 26 new toxic substances and mixtures containing them before the effective date, shall complete relevant obligations under the Chemical Control Act (K-CCA) within the deadlines specified. More specifically,
By January 1, 2026
Manufactures or importers shall submit a ‘Written Confirmation of Verification on Chemical Products’ as per Article 9 of K-CCA.
Handlers shall complete updating the labels of these toxic substances as per Article 16 of K-CCA.
Importers shall submit importation notification as per Article 20 of K-CCA.
By July 1, 2026
Handlers shall meet the criteria for handling toxic substances as per Article 13 of K-CCA and Annex 1 of K-CCA Enforcement Rules.
By July 1, 2027
Enterprises who install and operate relevant handling facilities shall prepare the chemical accident management plan as per Article 23 of K-CCA.
Handlers shall obtain the corresponding business license as per Article 28 of K-CCA.
By July 1, 2029
Enterprises which install and operate relevant handling facilities shall meet the standards for the establishment and management of such handling facilities as per Article 24 of K-CCA and Annex 5 of K-CCA Enforcement Rules.
Updates to GHS Classification List
The corresponding classification information, pictogram, signal words, hazard statements, M factors and UN No., etc. of 26 newly designated toxic substances (Given No. 2025-1-1223 ~ 2025-1-1248) are made public by NICS Announcement No. 2025-3.
The classification information of one listed toxic chemical Given No. 2019-1-956 has been updated as the figure below shows.

The last updates to these two lists were made on August 30, 2024 (CL news).


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